Immunolight, LLC Announces Expansion of its Phase 1 Trial to All Solid Tumor Types

Immunolight LLC, a clinical stage biopharmaceutical firm leading the way in advancing technologies to transform cancer treatment, is excited to announce that its X-PACT 101 Phase 1 Clinical Trial is now open to patients with all Solid Tumors types. The phase 1 study of its X-Ray Activation of Psoralen Cancer Treatment system (X-PACT) in Breast, Melanoma, Sarcoma, and Head and Neck Cancers has now been expanded to include patients with any type of Solid Tumor. Reach out to Immunolight on its social media (LinkedIn, Facebook; and Instagram), or through the Immunolight website immunolight.com for more information about how to navigate participation in this clinical trial!

The Immunolight X-PACT system uses a combination of 8-MOP a plant derived molecule (also known as 8-methoxypsoralen or methoxsalen) and the innovative Immunolight energy converting (EC) materials that convert deeply penetrating energies, such as low dose X-ray, into UV light inside solid tumors in the body. The (EC) materials and 8-MOP are co-injected into a solid tumor, and low dose x-ray energy is applied at the site making it a targeted treatment. The EC materials convert the applied x-ray into UV light which activates the 8-MOP inside the solid tumor to kill cancerous cells.

Specific details about the updated Phase 1 trial eligibility criteria and trial locations can be found on the ClinicalTrials.gov website: https://clinicaltrials.gov/ct2/show/NCT04389281

“This expansion of our Phase I trial to include all solid tumor types will open up our trial to many more patients, which has been our top priority from the beginning,” Immunolight founder and CEO Rick Bourke said.

President Harold Walder commented, "We are thrilled to open up our Phase I trial to a greater patient population, and use our paradigm changing cancer treatment to treat solid tumors of any origin."

Recruiting Patients for Phase 1 Trial of the X-PACT System in Certain Solid Tumors

Immunolight LLC, a clinical stage biopharmaceutical firm leading the way in advancing technologies to transform cancer treatment, announced today it is now recruiting patients for a Phase 1 study of its X-PACT Cancer Treatment system in advanced in Breast, Melanoma, Sarcoma, and Head and Neck Cancers.

The heart of the X-PACT system is 8-MOP (also known as 8-methoxypsoralen or methoxsalen) which has been successfully used for decades in the treatment of autoimmune disease, skin disorders and certain skin and blood cancers. However, since UV light, which is needed to activate 8-MOP, cannot penetrate through tissue, it has not been possible to use 8-MOP to treat solid tumors.  Immunolight's X-PACT system solves this problem.  Innovative Immunolight phosphor materials convert tissue penetrating energies, such as low dose X-ray, into UV light inside solid tumors in the body.  These energy converting phosphors are injected along with 8-MOP into the solid tumor, and low dose x-ray energy is applied at the site.  The phosphors convert the x-ray into UV light which activates the 8-MOP inside the solid tumor to kill the cancer.

More details about the Phase 1 trial and eligibility criteria can be found at https://clinicaltrials.gov/ct2/show/NCT04389281. 

Immunolight founder and CEO Rick Bourke commented, "We are thrilled to start patient recruitment and begin this Phase 1 trial, bringing our innovative technology to fruition in treating cancer and starting what we believe is a new era in cancer treatment."

This milestone is the culmination of over 13 years of intense research and development in partnership with Duke University and Duke Medical Center where a team of over 30 scientists, physicians and engineers has been active.  "From day one, our highest priority has been to translate this amazing science into a paradigm changing cancer treatment in patients," President Harold Walder said. "We are so excited to take this next step to get the treatment into the clinic."